![]() MCAT Practice Question #3Ĭategory: Psychological, Social, and Biological Foundations Methylation is an epigenetic modification that generally trends toward silencing gene expression. Histone deacetyltransferase (HDAC) binds DNA more tightly to histone, creating more heterochromatin, which is not expressed. Although in the real world these methods are not exclusive to increasing or decreasing activity, for MCAT testing purposes, histone acetyltransferase (HAT) frees DNA from histone proteins for expression.
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